Global interactions

Here, you can explore and compare overall interaction scores between all populations to identify which groups communicate the most with each other.

Select a dataset, heterogeneity level, score type, and ligand feature. The tool will then display the interaction network visualization.

Hold Ctrl/Cmd to select/deselect multiple
Leave empty to select all populations - Hold Ctrl/Cmd to select/deselect multiple
Leave empty to select all populations - Hold Ctrl/Cmd to select/deselect multiple
Interactions between given populations

Here, you can focus on communication between a chosen source and target population.

Select the source and target populations, along with the dataset, heterogeneity level, score type, and ligand feature. The tool will then display the most active ligand–receptor pairs driving the interaction between these populations, based on your selected score range.

Hold Ctrl/Cmd to select/deselect multiple
Leave empty to select all populations - Hold Ctrl/Cmd to select/deselect multiple
Leave empty to select all populations - Hold Ctrl/Cmd to select/deselect multiple
Interactions through specific ligand-receptor pair

Here, you can focus on a specific ligand–receptor pair.

Select the pair, along with the dataset, heterogeneity level, and score type. The tool will display in which populations this pair is most active, based on your selected score range.

Hold Ctrl/Cmd to select/deselect multiple
Type to search and select ligand-receptor pairs